Genome Wide Association Identifies PPFIA1 as a Candidate Gene for Acute Lung Injury Risk Following Major Trauma

Acute Lung Injury (ALI) is a syndrome with high associated mortality characterized by severe hypoxemia and pulmonary infiltrates in patients with critical illness. We conducted the first investigation to use the genome wide association (GWA) approach to identify putative risk variants for ALI. Genom...

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Hlavní autoři: Christie, Jason D., Wurfel, Mark M., Feng, Rui, O'Keefe, Grant E., Bradfield, Jonathan, Ware, Lorraine B., Christiani, David C., Calfee, Carolyn S., Cohen, Mitchell J., Matthay, Michael, Meyer, Nuala J., Kim, Cecilia, Li, Mingyao, Akey, Joshua, Barnes, Kathleen C., Sevransky, Jonathan, Lanken, Paul N., May, Addison K., Aplenc, Richard, Maloney, James P., Hakonarson, Hakon
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266233/
https://ncbi.nlm.nih.gov/pubmed/22295056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028268
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