ANGPT2 Genetic Variant Is Associated with Trauma-associated Acute Lung Injury and Altered Plasma Angiopoietin-2 Isoform Ratio

Rationale: Acute lung injury (ALI) acts as a complex genetic trait, yet its genetic risk factors remain incompletely understood. Large-scale genotyping has not previously been reported for ALI. Objectives: To identify ALI risk variants after major trauma using a large-scale candidate gene approach....

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Detalhes bibliográficos
Main Authors: Meyer, Nuala J., Li, Mingyao, Feng, Rui, Bradfield, Jonathan, Gallop, Robert, Bellamy, Scarlett, Fuchs, Barry D., Lanken, Paul N., Albelda, Steven M., Rushefski, Melanie, Aplenc, Richard, Abramova, Helen, Atochina-Vasserman, Elena N., Beers, Michael F., Calfee, Carolyn S., Cohen, Mitchell J., Pittet, Jean-Francois, Christiani, David C., O'Keefe, Grant E., Ware, Lorraine B., May, Addison K., Wurfel, Mark M., Hakonarson, Hakon, Christie, Jason D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
Assuntos:
B. Critical Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114062/
https://ncbi.nlm.nih.gov/pubmed/21257790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201005-0701OC
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