Homozygosity for the Toll-Like Receptor 2 R753Q Single-Nucleotide Polymorphism Is a Risk Factor for Cytomegalovirus Disease After Liver Transplantation

Immunity against cytomegalovirus (CMV) is initiated after its recognition by Toll-like receptor 2 (TLR2). We assessed the association between a single-nucleotide polymorphism (SNP) that impairs TLR2 function and CMV disease in a cohort of 737 liver recipients. Ninety-two of 737 patients (7.1%, 10.9%...

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Detalhes bibliográficos
Main Authors: Kang, Seung H., Abdel-Massih, Rima C., Brown, Robert A., Dierkhising, Ross A., Kremers, Walter K., Razonable, Raymund R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266129/
https://ncbi.nlm.nih.gov/pubmed/22219347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir819
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