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R753Q Single Nucleotide Polymorphism Impairs Toll-like Receptor 2 Recognition of Hepatitis C Virus Core and Nonstructural 3 Proteins
BACKGROUND: Hepatitis C virus (HCV) core and nonstructural 3 (NS3) proteins induce inflammation and immunity through a Toll-like receptor 2 (TLR2)-dependent pathway. Individuals with the R753Q single nucleotide polymorphism (SNP) in the TLR2 gene have increased risk of allograft failure after liver...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857328/ https://ncbi.nlm.nih.gov/pubmed/20090572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181cbac18 |
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