Leptin Promotes Fibroproliferative Acute Respiratory Distress Syndrome by Inhibiting Peroxisome Proliferator–activated Receptor-γ

Rationale: Diabetic patients have a lower incidence of acute respiratory distress syndrome (ARDS), and those who develop ARDS are less likely to die. The mechanisms that underlie this protection are unknown. Objectives: To determine whether leptin resistance, a feature of diabetes, prevents fibropro...

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Main Authors: Jain, Manu, Budinger, G. R. Scott, Lo, Amy, Urich, Daniela, Rivera, Stephanie E., Ghosh, Asish K., Gonzalez, Angel, Chiarella, Sergio E., Marks, Katie, Donnelly, Helen K., Soberanes, Saul, Varga, John, Radigan, Kathryn A., Chandel, Navdeep S., Mutlu, Gökhan M.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2011
Teme:
B. Critical Care
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266063/
https://ncbi.nlm.nih.gov/pubmed/21317313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201009-1409OC
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