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Mutual exclusivity analysis identifies oncogenic network modules

Although individual tumors of the same clinical type have surprisingly diverse genomic alterations, these events tend to occur in a limited number of pathways, and alterations that affect the same pathway tend to not co-occur in the same patient. While pathway analysis has been a powerful tool in ca...

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Hlavní autoři: Ciriello, Giovanni, Cerami, Ethan, Sander, Chris, Schultz, Nikolaus
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266046/
https://ncbi.nlm.nih.gov/pubmed/21908773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.125567.111
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