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Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription
Chromosomal translocations involving transcription factor genes have been identified in an increasingly wide range of cancers. Some translocations can create a protein “chimera” that is composed of parts from different proteins. How such chimeras cause cancer, and why they cause cancer in some cell...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266033/ https://ncbi.nlm.nih.gov/pubmed/22086061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.125666.111 |
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