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Ras, PI3K/Akt and senescence: Paradoxes provide clues for pancreatic cancer therapy

Pancreatic cancer is a leading cause of cancer-related death in the western world, and in most patients, current chemotherapies have negligible survival benefit. Evaluation of targeted therapies, however, is a relatively recent development. Paradoxically, mutations in KRAS, and in genes involved in...

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Detalhes bibliográficos
Main Authors: Kennedy, Alyssa L, Adams, Peter D, Morton, Jennifer P
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265817/
https://ncbi.nlm.nih.gov/pubmed/22292129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.5.17367
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