טוען...
Deletion of the oxygen-dependent degradation domain results in impaired transcriptional activity of hypoxia-inducible factors
Hypoxia-inducible factors (HIF1α/HIF2α) are key transcription factors that promote angiogenesis. The overexpression of degradation-resistant HIF mutants is considered a promising pro-angiogenic therapeutic tool. We compared the transcriptional activity of HIF1α/HIF2α mutants that obtained their resi...
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| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Landes Bioscience
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265788/ https://ncbi.nlm.nih.gov/pubmed/22223045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.2.6.18619 |
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