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Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints
INTRODUCTION: Chondrocytes have to withstand considerable hypoxic conditions within the avascular articular cartilage. The present study investigated the effects of inhibiting or stabilizing hypoxia-inducible factor (HIF)-1α by 2-methoxyestradiol or dimethyloxaloylglycine on the progression of osteo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592793/ https://ncbi.nlm.nih.gov/pubmed/18789153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2508 |
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