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P2X receptor antagonists for pain management: examination of binding and physicochemical properties

Enhanced sensitivity to noxious stimuli and the perception of non-noxious stimuli as painful are hallmark sensory perturbations associated with chronic pain. It is now appreciated that ATP, through its actions as an excitatory neurotransmitter, plays a prominent role in the initiation and maintenanc...

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Hlavní autoři: Gum, Rebecca J., Wakefield, Brian, Jarvis, Michael F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265705/
https://ncbi.nlm.nih.gov/pubmed/22086553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-011-9272-5
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