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Are Either or Both Hyperuricemia and Xanthine Oxidase Directly Toxic to the Vasculature? A critical appraisal

Basic research and clinical studies have implicated a role for hyperuricemia and for xanthine oxidoreductase (XOR), the enzyme that generates uric acid (UA), in not only gout but also vascular diseases. At present, asymptomatic hyperuricemia (i.e., in the absence of gout, urate nephrolithiasis, or t...

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Main Authors: Neogi, Tuhina, George, Jacob, Rekhraj, Sushma, Struthers, Allan D., Choi, Hyon, Terkeltaub, Robert A.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265683/
https://ncbi.nlm.nih.gov/pubmed/21953377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33369
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