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Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress

Oxidative stress plays an important role in the progression of vascular endothelial dysfunction. The two major systems generating vascular oxidative stress are the NADPH oxidase and the xanthine oxidase pathways. Allopurinol, a xanthine oxidase inhibitor, has been in clinical use for over 40 years i...

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Bibliografske podrobnosti
Main Authors: George, Jacob, Struthers, Allan D
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672460/
https://ncbi.nlm.nih.gov/pubmed/19436671
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