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miR-16 Targets Transcriptional Corepressor SMRT and Modulates NF-kappaB-Regulated Transactivation of Interleukin-8 Gene

The signaling pathways associated with the Toll-like receptors (TLRs) and nuclear factor-kappaB (NF-κB) are essential to pro-inflammatory cytokine and chemokine expression, as well as initiating innate epithelial immune responses. The TLR/NF-κB signaling pathways must be stringently controlled throu...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhou, Rui, Li, Xiaoqing, Hu, Guoku, Gong, Ai-Yu, Drescher, Kristen M., Chen, Xian-Ming
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265513/
https://ncbi.nlm.nih.gov/pubmed/22292036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030772
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