Plasmid-Cured Chlamydia caviae Activates TLR2-Dependent Signaling and Retains Virulence in the Guinea Pig Model of Genital Tract Infection

Loss of the conserved “cryptic” plasmid from C. trachomatis and C. muridarum is pleiotropic, resulting in reduced innate inflammatory activation via TLR2, glycogen accumulation and infectivity. The more genetically distant C. caviae GPIC is a natural pathogen of guinea pigs and induces upper genital...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Frazer, Lauren C., Darville, Toni, Chandra-Kuntal, Kumar, Andrews, Charles W., Zurenski, Matthew, Mintus, Margaret, AbdelRahman, Yasser M., Belland, Robert J., Ingalls, Robin R., O'Connell, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265510/
https://ncbi.nlm.nih.gov/pubmed/22292031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030747
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados