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IL-23 induces IL-22 and IL-17 production in response to Chlamydia muridarum genital tract infection, but the absence of these cytokines does not influence disease pathogenesis

OBJECTIVE: Chlamydia trachomatis Infections are a significant cause of reproductive tract pathology. Protective and pathologic immune mediators must be differentiated in order to design a safe and effective vaccine. METHODS: Wild-type mice and mice deficient in IL-22 and IL-23 were infected intravag...

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Detalhes bibliográficos
Main Authors: Frazer, Lauren C., Scurlock, Amy M., Zurenski, Matthew A., Riley, Melissa M., Mintus, Margaret, Pociask, Derek A., Sullivan, Jeanne E., Andrews, Charles W., Darville, Toni
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852156/
https://ncbi.nlm.nih.gov/pubmed/24238108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.12171
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