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Reproducible and Sustained Regulation of Gαs Signalling Using a Metazoan Opsin as an Optogenetic Tool

Originally developed to regulate neuronal excitability, optogenetics is increasingly also used to control other cellular processes with unprecedented spatiotemporal resolution. Optogenetic modulation of all major G-protein signalling pathways (Gq, Gi and Gs) has been achieved using variants of mamma...

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Detalhes bibliográficos
Main Authors: Bailes, Helena J., Zhuang, Ling-Yu, Lucas, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265508/
https://ncbi.nlm.nih.gov/pubmed/22292038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030774
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