Suppression of p75 Neurotrophin Receptor Surface Expression with Intrabodies Influences Bcl-xL mRNA Expression and Neurite Outgrowth in PC12 Cells

BACKGROUND: Although p75 neurotrophin receptor (p75NTR) is the first neurotrophin receptor isolated, its diverse physiological functions and signaling have remained elusive for many years. Loss-of-function phenotypic analyses for p75NTR were mainly focused at the genetic level; however these approac...

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Hlavní autoři: Zhang, Congcong, Helmsing, Saskia, Zagrebelsky, Marta, Schirrmann, Thomas, Marschall, Andrea L. J., Schüngel, Manuela, Korte, Martin, Hust, Michael, Dübel, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265506/
https://ncbi.nlm.nih.gov/pubmed/22292018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030684
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