Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

Dendritic cells (DCs) are the most potent APCs. Whereas immature DCs down-regulate T-cell responses to induce/maintain immunologic tolerance, mature DCs promote immunity. To amplify their functions, DCs communicate with neighboring DCs through soluble mediators, cell-to-cell contact, and vesicle exc...

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Main Authors: Montecalvo, Angela, Larregina, Adriana T., Shufesky, William J., Beer Stolz, Donna, Sullivan, Mara L. G., Karlsson, Jenny M., Baty, Catherine J., Gibson, Gregory A., Erdos, Geza, Wang, Zhiliang, Milosevic, Jadranka, Tkacheva, Olga A., Divito, Sherrie J., Jordan, Rick, Lyons-Weiler, James, Watkins, Simon C., Morelli, Adrian E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265200/
https://ncbi.nlm.nih.gov/pubmed/22031862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-338004
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