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Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

Dendritic cells (DCs) are the most potent APCs. Whereas immature DCs down-regulate T-cell responses to induce/maintain immunologic tolerance, mature DCs promote immunity. To amplify their functions, DCs communicate with neighboring DCs through soluble mediators, cell-to-cell contact, and vesicle exc...

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Detalles Bibliográficos
Autores principales: Montecalvo, Angela, Larregina, Adriana T., Shufesky, William J., Beer Stolz, Donna, Sullivan, Mara L. G., Karlsson, Jenny M., Baty, Catherine J., Gibson, Gregory A., Erdos, Geza, Wang, Zhiliang, Milosevic, Jadranka, Tkacheva, Olga A., Divito, Sherrie J., Jordan, Rick, Lyons-Weiler, James, Watkins, Simon C., Morelli, Adrian E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265200/
https://ncbi.nlm.nih.gov/pubmed/22031862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-338004
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