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Lack of Intestinal Epithelial Atg7 Affects Paneth Cell Granule Formation but Does Not Compromise Immune Homeostasis in the Gut

Genetic polymorphisms of autophagy-related genes have been associated with an increased risk to develop inflammatory bowel disease (IBD). Autophagy is an elementary process participating in several cellular events such as cellular clearance and nonapoptotic programmed cell death. Furthermore, autoph...

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Detalhes bibliográficos
Main Authors: Wittkopf, Nadine, Günther, Claudia, Martini, Eva, Waldner, Maximilian, Amann, Kerstin U., Neurath, Markus F., Becker, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265132/
https://ncbi.nlm.nih.gov/pubmed/22291845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/278059
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