Lack of Intestinal Epithelial Atg7 Affects Paneth Cell Granule Formation but Does Not Compromise Immune Homeostasis in the Gut

Genetic polymorphisms of autophagy-related genes have been associated with an increased risk to develop inflammatory bowel disease (IBD). Autophagy is an elementary process participating in several cellular events such as cellular clearance and nonapoptotic programmed cell death. Furthermore, autoph...

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Autors principals: Wittkopf, Nadine, Günther, Claudia, Martini, Eva, Waldner, Maximilian, Amann, Kerstin U., Neurath, Markus F., Becker, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265132/
https://ncbi.nlm.nih.gov/pubmed/22291845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/278059
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