A role for transcription from a piRNA cluster in de novo piRNA production

PIWI-interacting RNAs (piRNAs) are at the heart of the nucleic acid–based adaptive immune system against transposons in animal gonads. To date, how the piRNA pathway senses an element as a substrate and how de novo piRNA production is initiated remain elusive. Here, by utilizing a GFP transgene, we...

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Autores principales: Kawaoka, Shinpei, Mitsutake, Hiroshi, Kiuchi, Takashi, Kobayashi, Maki, Yoshikawa, Mayu, Suzuki, Yutaka, Sugano, Sumio, Shimada, Toru, Kobayashi, Jun, Tomari, Yukihide, Katsuma, Susumu
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264913/
https://ncbi.nlm.nih.gov/pubmed/22194309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.029777.111
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