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Computational reconstruction of multidomain proteins using atomic force microscopy data
Classical structural biology techniques face a great challenge to determine the structure at the atomic level of large and flexible macromolecules. We present a novel methodology that combines high-resolution AFM topographic images with atomic coordinates of proteins to assemble very large macromole...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264848/ https://ncbi.nlm.nih.gov/pubmed/22244760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.10.023 |
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