Computational reconstruction of multidomain proteins using atomic force microscopy data

Classical structural biology techniques face a great challenge to determine the structure at the atomic level of large and flexible macromolecules. We present a novel methodology that combines high-resolution AFM topographic images with atomic coordinates of proteins to assemble very large macromole...

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Hlavní autoři: Trinh, Minh-Hieu, Odorico, Michael, Pique, Michael E., Teulon, Jean-Marie, Roberts, Victoria A., Ten Eyck, Lynn F., Getzoff, Elizabeth D., Parot, Pierre, Chen, Shu-wen W., Pellequer, Jean-Luc
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264848/
https://ncbi.nlm.nih.gov/pubmed/22244760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.10.023
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