The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and neuroinflammation in the rat brain

BACKGROUND: Manganese (Mn) is a naturally occurring element and an essential nutrient for humans and animals. However, exposure to high levels of Mn may cause neurotoxic effects. The pathological mechanisms associated with Mn neurotoxicity are poorly understood, but several reports have established...

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Main Authors: Santos, Dinamene, Milatovic, Dejan, Andrade, Vanda, Camila, Batoreu M., Aschner, Michael, Marreilha dos Santos, A.P.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264815/
https://ncbi.nlm.nih.gov/pubmed/22154916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2011.11.017
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