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The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and neuroinflammation in the rat brain

BACKGROUND: Manganese (Mn) is a naturally occurring element and an essential nutrient for humans and animals. However, exposure to high levels of Mn may cause neurotoxic effects. The pathological mechanisms associated with Mn neurotoxicity are poorly understood, but several reports have established...

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Autori principali: Santos, Dinamene, Milatovic, Dejan, Andrade, Vanda, Camila, Batoreu M., Aschner, Michael, Marreilha dos Santos, A.P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264815/
https://ncbi.nlm.nih.gov/pubmed/22154916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2011.11.017
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