Rat brain endothelial cells are a target of manganese toxicity

Manganese (Mn) is an essential trace metal, however exposure to high Mn levels can result in neurodegenerative changes resembling Parkinson´s disease (PD). Information on Mn´s effects on endothelial cells of the blood-brain barrier (BBB) is lacking. Accordingly, we tested the hypothesis that BBB end...

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Main Authors: Marreilha dos Santos, Ana Paula, Milatovic, Dejan, Au, Catherine, Yin, Zhaobao, Batoreu, Maria Camila C., Aschner, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849855/
https://ncbi.nlm.nih.gov/pubmed/20170646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.02.016
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