Llwytho...

Synergistic Activity of Rapamycin and Dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis

Activation of the mTOR pathway subsequent to phosphatase and tensin homolog (PTEN) mutation may be associated with glucocorticoid (GC) resistance in acute lymphoblastic leukemia (ALL). The combination activity of rapamycin and dexamethasone in cell lines and xenograft models of ALL was determined. C...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhang, Chong, Ryu, Yong-Ku, Chen, Taylor Z., Hall, Connor P., Webster, Daniel R., Kang, Min H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264762/
https://ncbi.nlm.nih.gov/pubmed/22137317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2011.10.022
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