Efficacy of Combined Therapy with Amantadine, Oseltamivir, and Ribavirin In Vivo against Susceptible and Amantadine-Resistant Influenza A Viruses

The limited efficacy of existing antiviral therapies for influenza – coupled with widespread baseline antiviral resistance – highlights the urgent need for more effective therapy. We describe a triple combination antiviral drug (TCAD) regimen composed of amantadine, oseltamivir, and ribavirin that i...

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Detalhes bibliográficos
Main Authors: Nguyen, Jack T., Smee, Donald F., Barnard, Dale L., Julander, Justin G., Gross, Matthew, de Jong, Menno D., Went, Gregory T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264642/
https://ncbi.nlm.nih.gov/pubmed/22292088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031006
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