Novel Strategy for Selection of Monoclonal Antibodies Against Highly Conserved Antigens: Phage Library Panning Against Ephrin-B2 Displayed on Yeast

Ephrin-B2 is predominately expressed in endothelium of arterial origin, involved in developmental angiogenesis and neovasculature formation through its interaction with EphB4. Despite its importance in physiology and pathological conditions, it has been challenging to produce monoclonal antibodies a...

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Main Authors: Gu, Xiaoling, Vedvyas, Yogindra, Chen, Xiaoyue, Kaushik, Tanwi, Hwang, Chang-Il, Hu, Xuebo, Nikitin, Alexander Y., Jin, Moonsoo M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264634/
https://ncbi.nlm.nih.gov/pubmed/22292016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030680
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