Novel Strategy for Selection of Monoclonal Antibodies Against Highly Conserved Antigens: Phage Library Panning Against Ephrin-B2 Displayed on Yeast

Ephrin-B2 is predominately expressed in endothelium of arterial origin, involved in developmental angiogenesis and neovasculature formation through its interaction with EphB4. Despite its importance in physiology and pathological conditions, it has been challenging to produce monoclonal antibodies a...

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Dettagli Bibliografici
Autori principali: Gu, Xiaoling, Vedvyas, Yogindra, Chen, Xiaoyue, Kaushik, Tanwi, Hwang, Chang-Il, Hu, Xuebo, Nikitin, Alexander Y., Jin, Moonsoo M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264634/
https://ncbi.nlm.nih.gov/pubmed/22292016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030680
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