Effects of dilution and prolonged storage with preservative in a polyethylene container on Bevacizumab (Avastin™) for topical delivery as a nasal spray in anti-hereditary hemorrhagic telangiectasia and related therapies

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplasia and severe, recurrent epistaxis is a common clinical phenotype associated with HHT. An intranasal treatment regime of diluted Avastin™ (Bevacizumab; recombinant humanized anti-vascular epithelial growth factor im...

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Autores principales: Kaja, Simon, Hilgenberg, Jill D., Everett, Eric, Olitsky, Scott E., Gossage, Jim, Koulen, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264393/
https://ncbi.nlm.nih.gov/pubmed/22129679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/HAB-2011-0244
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