ELLIPSE Study: A Phase 1 study evaluating the tolerance of bevacizumab nasal spray in the treatment of epistaxis in hereditary hemorrhagic telangiectasia

Background: Hereditary hemorrhagic telangiectasia (HHT) is a dominantly inherited genetic vascular disorder in which epistaxis is the most frequent manifestation, responsible for high morbidity. Management of this symptom has no standard, and local treatments are often aggressive. Their efficacy is...

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Hlavní autoři: Dupuis-Girod, Sophie, Ambrun, Alexis, Decullier, Evelyne, Samson, Géraldine, Roux, Adeline, Fargeton, Anne-Emmanuelle, Rioufol, Catherine, Schwiertz, Verane, Disant, François, Chapuis, François, Donazzolo, Yves, Paintaud, Gilles, Edery, Patrick, Faure, Frederic
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011923/
https://ncbi.nlm.nih.gov/pubmed/24481211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.28025
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