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Blood, Tissue, and Intracellular Concentrations of Erythromycin and Its Metabolite Anhydroerythromycin during and after Therapy

For macrolides, clinical activity but also the development of bacterial resistance has been attributed to prolonged therapeutic and subtherapeutic concentrations. Although erythromycin is a long-established antimicrobial, concomitant determination of the pharmacokinetics of erythromycin and its meta...

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Главные авторы: Krasniqi, S., Matzneller, P., Kinzig, M., Sörgel, F., Hüttner, S., Lackner, E., Müller, M., Zeitlinger, M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264267/
https://ncbi.nlm.nih.gov/pubmed/22083477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05490-11
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