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Characterization of the Inhibition Mechanism of HIV-1 Nucleocapsid Protein Chaperone Activities by Methylated Oligoribonucleotides

Since currently available therapies against HIV/AIDS still show important drawbacks, the development of novel anti-HIV treatments is a key issue. We recently characterized methylated oligoribonucleotides (mONs) that extensively inhibit HIV-1 replication in primary T cells at nanomolar concentrations...

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Autori principali: Avilov, Sergiy V., Boudier, Christian, Gottikh, Marina, Darlix, Jean-Luc, Mély, Yves
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264206/
https://ncbi.nlm.nih.gov/pubmed/22083480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05614-11
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