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In Vitro Activity of JPC 2067 Alone and in Combination with Sulfamethoxazole against Nocardia Species

JPC 2067 is a novel dihydrotriazine dihydrofolate reductase inhibitor that is being developed as an antimalarial therapeutic. We evaluated the in vitro activity of JPC 2067 alone and in combination with sulfamethoxazole (SMX) against a panel of nocardia isolates. The MIC(50)s and MIC(90)s for JPC 20...

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Bibliographic Details
Main Authors: Mookherjee, Swagatam, Shoen, Carolyn, Cynamon, Michael
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264205/
https://ncbi.nlm.nih.gov/pubmed/22106219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05855-11
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