Improvement of the Redox Balance Increases l-Valine Production by Corynebacterium glutamicum under Oxygen Deprivation Conditions

Production of l-valine under oxygen deprivation conditions by Corynebacterium glutamicum lacking the lactate dehydrogenase gene ldhA and overexpressing the l-valine biosynthesis genes ilvBNCDE was repressed. This was attributed to imbalanced cofactor production and consumption in the overall l-valin...

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Autors principals: Hasegawa, Satoshi, Uematsu, Kimio, Natsuma, Yumi, Suda, Masako, Hiraga, Kazumi, Jojima, Toru, Inui, Masayuki, Yukawa, Hideaki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Biotechnology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264131/
https://ncbi.nlm.nih.gov/pubmed/22138982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.07056-11
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