Φορτώνει......
Carboxylesterases 1 and 2 Hydrolyze Phospho-Nonsteroidal Anti-Inflammatory Drugs: Relevance to Their Pharmacological Activity
Phospho-nonsteroidal anti-inflammatory drugs (phospho-NSAIDs) are novel NSAID derivatives with improved anticancer activity and reduced side effects in preclinical models. Here, we studied the metabolism of phospho-NSAIDs by carboxylesterases and assessed the impact of carboxylesterases on the antic...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263964/ https://ncbi.nlm.nih.gov/pubmed/22085648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.188508 |
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