Φορτώνει......

Carboxylesterases 1 and 2 Hydrolyze Phospho-Nonsteroidal Anti-Inflammatory Drugs: Relevance to Their Pharmacological Activity

Phospho-nonsteroidal anti-inflammatory drugs (phospho-NSAIDs) are novel NSAID derivatives with improved anticancer activity and reduced side effects in preclinical models. Here, we studied the metabolism of phospho-NSAIDs by carboxylesterases and assessed the impact of carboxylesterases on the antic...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wong, Chi C., Cheng, Ka-Wing, Xie, Gang, Zhou, Dingying, Zhu, Cai-Hua, Constantinides, Panayiotis P., Rigas, Basil
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Pharmacology and Experimental Therapeutics 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263964/
https://ncbi.nlm.nih.gov/pubmed/22085648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.188508
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