Hyperplastic Polyps Are Innocuous Lesions in Hereditary Nonpolyposis Colorectal Cancers

Aims. To compare methylation profiles, protein expression, and microsatellite instability (MSI) of sporadic, HNPCC, and familial hyperplastic polyps (HPs). Methods. Methylation-specific PCR (MSP) and pyrosequencing assessed p16, MGMT, hMLH-1, MINT 1, and MINT 31 methylation. IHC (Immunohistochemistr...

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Autors principals: Speake, D., O'Sullivan, J., Evans, D. G., Lalloo, F., Hill, J., McMahon, R. F. T.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263654/
https://ncbi.nlm.nih.gov/pubmed/22312515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/653163
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