Hyperplastic Polyps Are Innocuous Lesions in Hereditary Nonpolyposis Colorectal Cancers

Aims. To compare methylation profiles, protein expression, and microsatellite instability (MSI) of sporadic, HNPCC, and familial hyperplastic polyps (HPs). Methods. Methylation-specific PCR (MSP) and pyrosequencing assessed p16, MGMT, hMLH-1, MINT 1, and MINT 31 methylation. IHC (Immunohistochemistr...

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Detalhes bibliográficos
Main Authors: Speake, D., O'Sullivan, J., Evans, D. G., Lalloo, F., Hill, J., McMahon, R. F. T.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263654/
https://ncbi.nlm.nih.gov/pubmed/22312515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/653163
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