A Single Dose of Oral BCG Moreau Fails to Boost Systemic IFN-γ Responses to Tuberculin in Children in the Rural Tropics: Evidence for a Barrier to Mucosal Immunization

Immune responses to oral vaccines are impaired in populations living in conditions of poverty in developing countries, and there is evidence that concurrent geohelminth infections may contribute to this effect. We vaccinated 48 children living in rural communities in Ecuador with a single oral dose...

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Autors principals: Vaca, Maritza, Moncayo, Ana-Lucia, Cosgrove, Catherine A., Chico, Martha E., Castello-Branco, Luiz R., Lewis, David J., Cooper, Philip J.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Clinical Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263634/
https://ncbi.nlm.nih.gov/pubmed/22287972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/132583
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