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Development of an Oral Form of Azacytidine: 2′3′5′Triacetyl-5-Azacytidine

Myelodysplastic syndromes (MDSs) represent a group of incurable stem-cell malignancies which are predominantly treated by supportive care. Epigenetic silencing through promoter methylation of a number of genes is present in poor-risk subtypes of MDS and often predicts transformation to acute myeloge...

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Detalhes bibliográficos
Main Authors: Ziemba, Amy, Hayes, Eugene, Freeman, Burgess B., Ye, Tao, Pizzorno, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263612/
https://ncbi.nlm.nih.gov/pubmed/22295208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/965826
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