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Chemical synthesis of 5-azacytidine nucleotides and preparation of tRNAs containing 5-azacytidine in its 3'-terminus.

5-azacytidine-5'-triphosphate prepared from 5-azacytidine by chemical phosphorylation is a substrate for AMP (CMP) tRNA nucleotidyl transferase from yeast. tRNAsPhe from yeast containing 5-azacytidine in their 3'-termini were prepared enzymatically. tRNAPhe-Cpn5CpA and tRNAPhe-n5Cpn5CpA ca...

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Detalhes bibliográficos
Main Authors: Zielinski, W S, Sprinzl, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC318897/
https://ncbi.nlm.nih.gov/pubmed/6204276
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