Role of Rho Kinase Isoforms in Murine Allergic Airway Responses

OBJECTIVE: Inhibition of Rho-associated coiled-coil forming kinases (ROCKs) reduces allergic airway responses in mice. The purpose of this study was to determine the roles of the two ROCK isoforms, ROCK1 and ROCK2, in these responses. METHODS: Wildtype mice and heterozygous ROCK1 and ROCK2 knockout...

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Hoofdauteurs: Zhu, Ming, Liu, Ping-Yen, Kasahara, David I., Williams, Alison S., Verbout, Norah G., Halayko, Andrew J., Fedulov, Alexey, Shoji, Takuhito, Williams, Erin S., Noma, Kensuke, Shore, Stephanie A., Liao, James K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263528/
https://ncbi.nlm.nih.gov/pubmed/21565918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00125010
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