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Jagged2 controls the generation of motor neuron and oligodendrocyte progenitors in the ventral spinal cord

In the developing spinal cord, motor neurons (MNs) and oligodendrocytes arise sequentially from a common pool of progenitors. However, the genetic network responsible for this neurogenesis to gliogenesis switch is largely unknown. A transcriptome analysis identified the Notch ligand Jagged2 (JAG2) a...

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Autors principals: Rabadán, M A, Cayuso, J, Le Dréau, G, Cruz, C, Barzi, M, Pons, S, Briscoe, J, Martí, E
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263496/
https://ncbi.nlm.nih.gov/pubmed/21720386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.84
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