In vitro and in vivo evaluation of ordered mesoporous silica as a novel adsorbent in liquisolid formulation

BACKGROUND: A liquisolid technique has been reported to be a new approach to improve the release of poorly water-soluble drugs for oral administration. However, an apparent limitation of this technique is the formulation of a high dose because a large amount of liquid vehicle is needed, which finall...

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Bibliographic Details
Main Authors: Chen, Bao, Wang, Zhouhua, Quan, Guilan, Peng, Xinsheng, Pan, Xin, Wang, Rongchang, Xu, Yuehong, Li, Ge, Wu, Chuanbin
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263412/
https://ncbi.nlm.nih.gov/pubmed/22275835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S26763
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