A novel folate-modified self-microemulsifying drug delivery system of curcumin for colon targeting

BACKGROUND: The objective of this study was to prepare, characterize, and evaluate a folate-modified self-microemulsifying drug delivery system (FSMEDDS) with the aim to improve the solubility of curcumin and its delivery to the colon, facilitating endocytosis of FSMEDDS mediated by folate receptors...

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Autores principales: Zhang, Lin, Zhu, Weiwei, Yang, Chunfen, Guo, Hongxia, Yu, Aihua, Ji, Jianbo, Gao, Yan, Sun, Min, Zhai, Guangxi
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2012
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263408/
https://ncbi.nlm.nih.gov/pubmed/22275831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S27639
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