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TSLP promotes IL-3-independent basophil hematopoiesis and type 2 inflammation

CD4(+) T helper type 2 (Th2) cells characterized by their expression of IL-4, IL-5, IL-9 and IL-13 are required for immunity to helminth parasites(1) and promote the pathological inflammation associated with asthma and allergic diseases(2). Polymorphisms in the gene encoding the cytokine thymic stro...

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Hlavní autoři: Siracusa, Mark C., Saenz, Steven A., Hill, David A., Kim, Brian S., Headley, Mark B., Doering, Travis A., Jessup, Heidi K., Siegel, Lori A., Kambayashi, Taku, Dudek, Emily C., Kubo, Masato, Cianferoni, Antonella, Spergel, Jonathan M., Ziegler, Steven F., Comeau, Michael R., Artis, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263308/
https://ncbi.nlm.nih.gov/pubmed/21841801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10329
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