Functional Promiscuity of the COG0720 Family

The biosynthesis of GTP derived metabolites such as tetrahydrofolate (THF), biopterin (BH(4)), and the modified tRNA nucleosides queuosine (Q) and archaeosine (G(+)) relies on several enzymes of the Tunnel-fold superfamily. A subset of these proteins include the 6-pyruvoyl-tetrahydropterin (PTPS-II)...

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Bibliographic Details
Main Authors: Phillips, Gabriela, Grochowski, Laura L., Bonnett, Shilah, Xu, Huimin, Bailly, Marc, Haas-Blaby, Crysten, El Yacoubi, Basma, Iwata-Reuyl, Dirk, White, Robert H., de Crécy-Lagard, Valérie
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262898/
https://ncbi.nlm.nih.gov/pubmed/21999246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200329f
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