Genomic Biomarkers of Phthalate-Induced Male Reproductive Developmental Toxicity: A Targeted RT-PCR Array Approach for Defining Relative Potency

Male rat fetuses exposed to certain phthalate esters (PEs) during sexual differentiation display reproductive tract malformations due to reductions in testosterone (T) production and the expression of steroidogenesis- and INSL3-related genes. In the current study, we used a 96-well real-time PCR arr...

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Detalhes bibliográficos
Main Authors: Hannas, Bethany R., Lambright, Christy S., Furr, Johnathan, Evans, Nicola, Foster, Paul M. D., Gray, Earl L., Wilson, Vickie S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Reproductive and Developmental Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262859/
https://ncbi.nlm.nih.gov/pubmed/22112501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr315
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