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Protein Kinase D1 Maintains the Epithelial Phenotype by Inducing a DNA-Bound, Inactive SNAI1 Transcriptional Repressor Complex

BACKGROUND: Protein Kinase D1 is downregulated in its expression in invasive ductal carcinoma of the breast and in invasive breast cancer cells, but its functions in normal breast epithelial cells is largely unknown. The epithelial phenotype is maintained by cell-cell junctions formed by E-cadherin....

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書誌詳細
主要な著者: Bastea, Ligia I., Döppler, Heike, Balogun, Bolanle, Storz, Peter
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262827/
https://ncbi.nlm.nih.gov/pubmed/22276203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030459
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